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Metabolism
The mitochondrial unfolded protein response inhibits pluripotency acquisition and mesenchymal-to-epithelial transition in somatic cell reprogramming
mitochondrial function
TMEM65 regulates and is required for NCLX-dependent mitochondrial calcium efflux
TMEM65
Hyperglycemia-triggered lipid peroxidation destabilizes STAT4 and impairs anti-viral Th1 responses in type 2 diabetes
type 2 diabetes
hyperglycemia
T helper 1 responses
lipid peroxidation
Misregulation of mitochondrial 6mA promotes the propagation of mutant mtDNA and causes aging in C. Elegans
6mA
mtDNA
mitochondrial genome
mitochondria
Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer
heterogeneity
fatty acid
Organization of a functional glycolytic metabolon on mitochondria for metabolic efficiency
mitochondria
glucose
glucose metabolism
Futile lipid cycling: from biochemistry to physiology
Metabolism
glyceride
PNPO–PLP axis senses prolonged hypoxia in macrophages by regulating lysosomal activity
PNPO
Lysine acetyltransferase 6A maintains CD4+ T cell response via epigenetic reprogramming of glucose metabolism in autoimmunity
glucose metabolism
histone acetylation
autoimmune
KAT6A
Mitochondrial fatty acid synthesis is an emergent central regulator of mammalian oxidative metabolism
mitochondria
mitochondrial fatty acid synthesis
mtFAS
fatty acids
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